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About Health Sciences Center at Prisma Health

About Us

Our mission is to improve health in South Carolina and beyond.

Since 1912, when Greenville City Hospital and its School of Nursing opened their doors, our organization has been deeply engaged in providing education and care to local communities. After decades of growth and transformation, including the formation of Prisma Health, our leadership recommended that we use our education and training strengths to pursue a novel variation of an academic health center. The Health Sciences Center was founded, combining Greenville’s longtime academic partners, a shared vision, a more structured organization, and a strategy for innovation in teaching, workforce development, research, and entrepreneurial activities.

About Health Sciences Center at Prisma Health

Health Sciences Center today

Today, the Health Sciences Center at Prisma Health is a robust academic center driven by our integrated healthcare delivery system. We create a synergy of academics, research, innovation, and healthcare practice to drive change – and we are unlike any other organization.

Grounded in a cooperative and applied approach, we are dedicated to developing new solutions in healthcare education, delivery, access, and affordability to help people live healthier, better lives across South Carolina and beyond.

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About our partners

How we’re different – our partners

Like a traditional academic health center, the Health Sciences Center at Prisma Health partners with South Carolina’s two largest research universities and most prominent liberal arts university. The center also includes programs for other health professions and a robust research and innovation agenda.

Where we differ is that we partner with multiple affiliate universities and degree-granting institutions. We leverage the existing competencies and resources of our partners, rather than duplicating costly infrastructures, to meet shared objectives. We are also the only academic medical center led by a health system, and our mission has a strong clinical focus rather than academic only. Additionally, we do not grant degrees but work collaboratively with our academic and clinical partners to bring more value to students, employers, and the community.

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A unique model for transformation

The Health Sciences Center takes an applied, real-world approach, combining academics, research, innovation, and practice.

8,000 students annually

Access the Prisma Health clinical environments to explore and train for healthcare careers

1,100 active research trials

Includes 400 clinical trials conducted across our clinical departments in Upstate and the Midlands

90+ embedded scientists

Working with Prisma clinicians to conduct research and drive innovation

62 residency and fellowships

Serving over 600 residents and cover multiple specializations

Four affiliated schools

Two affiliated medical schools, two affiliated nursing schools


More than 100 years of education and research

1912: Greenville City Hospital and School of Nursing open
1926: Greenville hosts first medical interns
1940s: Collaboration begins between Furman University and our School of Nursing
1961: Dr. Raymond C. Ramage named first Director of Medical Education in Greenville
1983: University of South Carolina and the Greenville Health System (GHS) affiliation agreement established
1990: Clemson University and GHS research and education agreement signed
1991: USC third- and fourth-year medical students begin full-time training at GHS
2000: First sub-specialty fellowship at GHS
2009: Certified Registered Nurse Anesthetist (CRNA) Program announced
2011: USC School of Medicine Greenville achieves LCME preliminary accreditation
2011: First full-time SC School of Pharmacy class at GHS
2012: USC School of Medicine Greenville’s charter class
2013: Legacy of education and research continues with GHS through formal partnerships with Clemson University, Furman University, and University of South Carolina
2014: GHS Clinical University is established and used as an umbrella for the innovative teaching, workforce development, research, and entrepreneurial activities conducted with academic partners
2016: USC School of Medicine Greenville’s charter class graduates; 2017 collaboration with Clemson University School of Nursing announced
2017: GHS Clinical University changes to the Health Sciences Center; Prisma Health is formed from GHS and Palmetto Health; Health Sciences Center Office of Innovation is founded